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The reinforcing effect and DA level induced by DNC + NIC were greater than the sum of the two parts, suggesting that the relationship of the DNC group to nicotine was synergistic rather than additive, and the synergistic effect was further supported by the unique enhancement of the DNC + NIC group in locomotor activity compared to the NIC group (Figure 2C) and anxiety performance (Figure 2D)

Nationally, adult smoking prevalence was 14.0%.1 In 2021, 3.7% of high school students in New Jersey smoked cigarettes on at least one day in the past 30 days

The 2018 Farm Bill legalized all hemp products federally as long as they to not contain more than 0.3% THC (the chemical that makes you high)

The Eggers test P-values were 0.512, 0.123 and 0.876 for the composite CVD, MI, and stroke outcomes, respectively